8VUI
Structure of FabS1CE-EPR-1, an elbow-locked Fab, in complex with the erythropoeitin receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S1CE VARIANT OF FAB-EPR-1 heavy chain | polymer | 224 | 24096.0 | 1 | Homo sapiens | ||
2 | G | S1CE VARIANT OF FAB-EPR-1 light chain | polymer | 212 | 23049.5 | 1 | Homo sapiens | ||
3 | D | Erythropoietin receptor | polymer | 232 | 25680.0 | 1 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (human) | EPO-R |
4 | A, G | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | A, G | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
6 | A, G, D | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
7 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
8 | D | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
9 | D | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
10 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
D: 1 - 226 (UniProt: P19235)
PDB | External Database | Details |
---|---|---|
His 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
His 230 | - | expression tag |
His 231 | - | expression tag |
His 232 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 72825.5 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 886.8 | |
All* | Total formula weight | 73712.3 |