8VHU
Crystal structure of dATP bound E. coli class Ia ribonucleotide reductase alpha construct fused with the C-terminal tail of E. coli class Ia beta subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fusion protein of Ribonucleoside-diphosphate reductase 1 subunits alpha and beta | polymer | 807 | 90940.4 | 2 | UniProt (P00452) UniProt (P69924) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Escherichia coli K-12 | |
| 2 | C, E, K (A, B) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 3 | Chemie (DTP) | |||
| 3 | D, F, L (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H, I, J, M, N... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 6 | P (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 1357 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 734 (UniProt: P00452)
A, B: 1341 - 1375 (UniProt: P69924)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Arg 735 | - | linker |
| Asp 736 | - | linker |
| Gly 737 | - | linker |
| Ala 1325 | - | linker |
| Glu 1326 | - | linker |
| Asp 1327 | - | linker |
| Ala 1328 | - | linker |
| Gln 1329 | - | linker |
| Asp 1330 | - | linker |
| Asp 1331 | - | linker |
| Leu 1332 | - | linker |
| Val 1333 | - | linker |
| Pro 1334 | - | linker |
| Ser 1335 | - | linker |
| Ile 1336 | - | linker |
| Gln 1337 | - | linker |
| Asp 1338 | - | linker |
| Asp 1339 | - | linker |
| Gly 1340 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 181880.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1874.3 | |
| All* | Total formula weight | 183755.0 |
