Functional Information from PROSITE/UniProt
site_id | PS00089 |
Number of Residues | 23 |
Details | RIBORED_LARGE Ribonucleotide reductase large subunit signature. WeaLresikthGLRNstlSAlmP |
Chain | Residue | Details |
A | TRP599-PRO621 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | ASN437 | |
A | GLU441 | |
B | ASN437 | |
B | GLU441 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Cysteine radical intermediate |
Chain | Residue | Details |
A | CYS439 | |
B | CYS439 | |
Chain | Residue | Details |
A | LYS9 | |
A | GLU15 | |
A | THR55 | |
A | LYS91 | |
B | LYS9 | |
B | GLU15 | |
B | THR55 | |
B | LYS91 | |
Chain | Residue | Details |
A | THR209 | |
B | ARG262 | |
B | ARG269 | |
B | ASN437 | |
B | GLU441 | |
B | GLU623 | |
A | ASP232 | |
A | ARG262 | |
A | ARG269 | |
A | ASN437 | |
A | GLU441 | |
A | GLU623 | |
B | THR209 | |
B | ASP232 | |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | SITE: Important for hydrogen atom transfer |
Chain | Residue | Details |
A | CYS225 | |
A | CYS462 | |
B | CYS225 | |
B | CYS462 | |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | SITE: Important for electron transfer |
Chain | Residue | Details |
A | TYR730 | |
A | TYR731 | |
B | TYR730 | |
B | TYR731 | |
Chain | Residue | Details |
A | LYS283 | |
B | LYS283 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 7 |
Details | M-CSA 918 |
Chain | Residue | Details |
A | CYS225 | proton donor |
A | ASN437 | |
A | CYS439 | hydrogen radical acceptor, hydrogen radical donor, single electron acceptor |
A | GLU441 | proton acceptor |
A | CYS462 | |
A | TYR730 | pi-pi interaction, single electron relay |
A | TYR731 | pi-pi interaction, single electron relay |
site_id | MCSA2 |
Number of Residues | 7 |
Details | M-CSA 918 |
Chain | Residue | Details |
B | CYS225 | proton donor |
B | ASN437 | |
B | CYS439 | hydrogen radical acceptor, hydrogen radical donor, single electron acceptor |
B | GLU441 | proton acceptor |
B | CYS462 | |
B | TYR730 | pi-pi interaction, single electron relay |
B | TYR731 | pi-pi interaction, single electron relay |