8VFV
HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G, C, M | RM20A3 Fab heavy chain | polymer | 125 | 13511.1 | 3 | Macaca mulatta (Rhesus monkey) | ||
2 | I, D, N | RM20A3 Fab light chain | polymer | 128 | 13508.8 | 3 | Macaca mulatta (Rhesus monkey) | ||
3 | E, A, J | Envelope glycoprotein gp120 | polymer | 481 | 54221.7 | 3 | UniProt (Q2N0S6) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | Env polyprotein |
4 | F, B, K | Transmembrane protein gp41 | polymer | 153 | 17134.3 | 3 | UniProt (Q2N0S6) Pfam (PF00517) In PDB | Human immunodeficiency virus 1 | TM, Glycoprotein 41, gp41 |
5 | H | B16_d77.5 mouse Fab heavy chain Fv | polymer | 130 | 13972.7 | 1 | Mus musculus (mouse) | ||
6 | L | B16_d77.5 mouse Fab light chain Fv | polymer | 111 | 12012.3 | 1 | Mus musculus (mouse) | ||
7 | O, R, U | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
8 | P, S, V | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
9 | Q, T, W | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
10 | E, J, K, F, A... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) |
Sequence modifications
E, A, J: 31 - 513 (UniProt: Q2N0S6)
F, B, K: 512 - 664 (UniProt: Q2N0S6)
PDB | External Database | Details |
---|---|---|
Glu 106 | Thr 105 | conflict |
Tyr 134 | Val 133 | conflict |
Glu 136 | Asn 135 | conflict |
Lys 137 | Asn 136 | conflict |
Leu 138 | Ile 137 | conflict |
Arg 139 | Thr 138 | conflict |
Ser 140 | Asp 139 | conflict |
Met 141 | Asp 140 | conflict |
Lys 151 | Arg 142 | conflict |
Ile 271 | Met 270 | conflict |
Leu 288 | Phe 287 | conflict |
Val 304 | Arg 303 | conflict |
Tyr 319 | Ala 316 | conflict |
His 325 | Asp 323 | conflict |
Asn 332 | Thr 330 | conflict |
Gln 363 | Asn 361 | conflict |
Cys 501 | Ala 498 | conflict |
Arg 509 | Glu 506 | conflict |
Arg 510 | Lys 507 | conflict |
Arg 512 | Ala 509 | conflict |
Arg 513 | Val 510 | conflict |
PDB | External Database | Details |
---|---|---|
Ser 519 | Phe 516 | conflict |
Pro 559 | Ile 556 | conflict |
Pro 561 | Ala 558 | conflict |
Asp 568 | Leu 565 | conflict |
His 570 | Val 567 | conflict |
His 585 | Arg 582 | conflict |
Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 14 |
Total formula weight | 321112.7 | |
Branched | Number of molecules | 9 |
Total formula weight | 6738.1 | |
Non-Polymers* | Number of molecules | 36 |
Total formula weight | 7963.5 | |
All* | Total formula weight | 335814.3 |