8UWC

Site-one protease without SPRING

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Membrane-bound transcription factor site-1 protease	polymer	1014	113883.8	1	UniProt (Q14703) Pfam (PF23001) Pfam (PF00082) In PDB	Homo sapiens (human)	Endopeptidase S1P,Subtilisin/kexin-isozyme 1,SKI-1
2	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3		water	water		18.0	97	Chemie (HOH)

Sequence modifications

A: 24 - 998 (UniProt: Q14703)

PDB	External Database	Details
Met -5	-	initiating methionine
Glu -4	-	expression tag
Thr -3	-	expression tag
Asp -2	-	expression tag
Thr -1	-	expression tag
Leu 0	-	expression tag
Leu 1	-	expression tag
Leu 2	-	expression tag
Trp 3	-	expression tag
Val 4	-	expression tag
Leu 5	-	expression tag
Leu 6	-	expression tag
Leu 7	-	expression tag
Trp 8	-	expression tag
Val 9	-	expression tag
Pro 10	-	expression tag
Gly 11	-	expression tag
Ser 12	-	expression tag
Thr 13	-	expression tag
Gly 14	-	expression tag
Asp 15	-	expression tag
Tyr 16	-	expression tag
Lys 17	-	expression tag
Asp 18	-	expression tag
Asp 19	-	expression tag
Asp 20	-	expression tag
Asp 21	-	expression tag
Lys 22	-	expression tag
Asp 23	-	expression tag
His 999	-	expression tag
His 1000	-	expression tag
His 1001	-	expression tag
His 1002	-	expression tag
His 1003	-	expression tag
His 1004	-	expression tag
His 1005	-	expression tag
His 1006	-	expression tag
His 1007	-	expression tag
His 1008	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	113883.8
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	114105.0

*Water molecules are not included.