8USS
IL17A complexed to Compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-17A | polymer | 127 | 14537.3 | 1 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (human) | IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | B (A) | 4,5-dichloro-N-[(1S)-1-cyclohexyl-2-{[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]amino}-2-oxoethyl]-1H-pyrrole-2-carboxamide | non-polymer | 493.4 | 1 | Chemie (XCW) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 34 - 155 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Met 32 | - | expression tag |
| Ala 33 | - | expression tag |
| Ser 129 | Cys 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14537.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 528.8 | |
| All* | Total formula weight | 15066.2 |
