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8USS

IL17A complexed to Compound 7

Functional Information from GO Data
ChainGOidnamespacecontents
A0002225biological_processpositive regulation of antimicrobial peptide production
A0002250biological_processadaptive immune response
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006915biological_processapoptotic process
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007219biological_processNotch signaling pathway
A0007267biological_processcell-cell signaling
A0008219biological_processcell death
A0009611biological_processresponse to wounding
A0009897cellular_componentexternal side of plasma membrane
A0010467biological_processgene expression
A0030216biological_processkeratinocyte differentiation
A0032731biological_processpositive regulation of interleukin-1 beta production
A0032735biological_processpositive regulation of interleukin-12 production
A0032739biological_processpositive regulation of interleukin-16 production
A0032747biological_processpositive regulation of interleukin-23 production
A0032755biological_processpositive regulation of interleukin-6 production
A0032760biological_processpositive regulation of tumor necrosis factor production
A0038173biological_processinterleukin-17A-mediated signaling pathway
A0042803molecular_functionprotein homodimerization activity
A0043616biological_processkeratinocyte proliferation
A0045087biological_processinnate immune response
A0045672biological_processpositive regulation of osteoclast differentiation
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046982molecular_functionprotein heterodimerization activity
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0050832biological_processdefense response to fungus
A0060729biological_processintestinal epithelial structure maintenance
A0071347biological_processcellular response to interleukin-1
A0072537biological_processfibroblast activation
A0097400biological_processinterleukin-17-mediated signaling pathway
A0097530biological_processgranulocyte migration
A0106015biological_processnegative regulation of inflammatory response to wounding
A1900017biological_processpositive regulation of cytokine production involved in inflammatory response
A1903348biological_processpositive regulation of bicellular tight junction assembly
A2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN68

219869

PDB entries from 2024-05-15

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