8USS

IL17A complexed to Compound 7

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	PIXEL
Collection date	2018-02-14
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.00
Spacegroup name	I 2 2 2
Unit cell lengths	36.600, 50.380, 157.360
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	15.780 - 1.470
R-factor	0.222
Rwork	0.221
R-free	0.23550
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.023
RMSD bond angle	2.092
Data reduction software	autoPROC
Data scaling software	autoPROC
Phasing software	PHASER
Refinement software	PHENIX (1.20.1_4487)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	78.700	1.526
High resolution limit [Å]	1.465	1.465
Number of reflections	21942	1098
<I/σ(I)>	21.9
Completeness [%]	85.6
Redundancy	5.1
CC(1/2)	1.000	0.880

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		296	15% w/v PEG 8K, 0.2 M MgCl2, 0.1 M Tris pH 8.5