8UO5

Protein Phosphatase 2A B55 subunit in complex with IER5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	polymer	613	68065.2	1	UniProt (P30153) Pfam (PF02985)	Homo sapiens (human)
2	B (B)	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	polymer	447	51762.0	1	UniProt (P63151)	Homo sapiens (human)
3	C (C)	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	polymer	332	38259.9	1	UniProt (P67775) Pfam (PF00149)	Homo sapiens (human)
4	D (D)	Immediate early response gene 5 protein	polymer	74	8532.8	1	UniProt (Q5VY09)	Homo sapiens (human)
5	E (C)	FE (III) ION	non-polymer		55.8	1	Chemie (FE)
6	F (C)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 1 - 589 (UniProt: P30153)

PDB	External Database	Details
Met -23	-	expression tag
Gly -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ala -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

C: 1 - 309 (UniProt: P67775)

PDB	External Database	Details
Met -22	-	expression tag
Asp -21	-	expression tag
Tyr -20	-	expression tag
Lys -19	-	expression tag
Asp -18	-	expression tag
Asp -17	-	expression tag
Asp -16	-	expression tag
Asp -15	-	expression tag
Lys -14	-	expression tag
Ser -13	-	expression tag
Ala -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

D: 1 - 50 (UniProt: Q5VY09)

PDB	External Database	Details
Met -23	-	expression tag
Asp -22	-	expression tag
Trp -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
Pro -18	-	expression tag
Gln -17	-	expression tag
Phe -16	-	expression tag
Glu -15	-	expression tag
Lys -14	-	expression tag
Ser -13	-	expression tag
Ala -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	166619.9
Non-Polymers*	Number of molecules	2
	Total formula weight	121.3
All*	Total formula weight	166741.2

*Water molecules are not included.