8UDC
Crystal structure of TcPINK1 in complex with CYC116
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Pink1, mitochondrial | polymer | 455 | 50898.1 | 1 | UniProt (D6WMX4) Pfam (PF00069) | Tribolium castaneum (red flour beetle) | |
| 2 | B (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | (4P)-4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine | non-polymer | 368.5 | 1 | Chemie (WCK) | |||
| 5 | E (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 121 - 570 (UniProt: D6WMX4)
| PDB | External Database | Details |
|---|---|---|
| Gly 116 | - | expression tag |
| Pro 117 | - | expression tag |
| Leu 118 | - | expression tag |
| Gly 119 | - | expression tag |
| Ser 120 | - | expression tag |
| Ala 131 | Trp 131 | engineered mutation |
| Ala 142 | Trp 142 | engineered mutation |
| Ala 144 | Tyr 144 | engineered mutation |
| Ala 147 | Ile 147 | engineered mutation |
| Ala 225 | Tyr 225 | engineered mutation |
| Ala 378 | Tyr 378 | engineered mutation |
| Ala 401 | Phe 401 | engineered mutation |
| Ala 437 | Phe 437 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50898.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.6 | |
| All* | Total formula weight | 51468.8 |
