8TVC
Crystal structure of rA3G-ssDNA-AA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DNA dC->dU-editing enzyme APOBEC-3G | polymer | 386 | 45199.6 | 1 | UniProt (M1GSK9) Pfam (PF18750) Pfam (PF18782) UniProt (by SIFTS) (Q7YR23) | Macaca mulatta (Rhesus monkey) | Deoxycytidine deaminase |
2 | B (B) | DNA 21-mer | polymer | 21 | 6371.1 | 1 | synthetic construct | ||
3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
5 | F, G (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 1 - 380 (UniProt: M1GSK9)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Gly -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Gly -1 | - | expression tag |
Gly 0 | - | expression tag |
- | Cys 139 | deletion |
- | Gln 140 | deletion |
- | Lys 141 | deletion |
- | Arg 142 | deletion |
Ala 139 | Asp 143 | conflict |
Glu 140 | Gly 144 | conflict |
Ala 141 | Pro 145 | conflict |
Gly 142 | His 146 | conflict |
Ala 259 | Glu 259 | conflict |
Ile 381 | - | cloning artifact |
Leu 382 | - | cloning artifact |
Gln 383 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51570.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 225.8 | |
All* | Total formula weight | 51796.5 |