8TVC
Crystal structure of rA3G-ssDNA-AA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000932 | cellular_component | P-body |
| A | 0002376 | biological_process | immune system process |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004126 | molecular_function | cytidine deaminase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0010526 | biological_process | transposable element silencing |
| A | 0016554 | biological_process | cytidine to uridine editing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0045071 | biological_process | negative regulation of viral genome replication |
| A | 0045087 | biological_process | innate immune response |
| A | 0045869 | biological_process | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
| A | 0070383 | biological_process | DNA cytosine deamination |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01083 |
| Chain | Residue | Details |
| A | LEU263 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36598981, ECO:0007744|PDB:8E40 |
| Chain | Residue | Details |
| A | HIS65 | |
| A | CYS97 | |
| A | CYS100 | |
| A | CYS261 | |
| A | ALA291 | |
| A | MET294 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Interaction with DNA => ECO:0000305 |
| Chain | Residue | Details |
| A | ASN248 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKA => ECO:0000250|UniProtKB:Q9HC16 |
| Chain | Residue | Details |
| A | THR32 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKA and CAMK2 => ECO:0000250|UniProtKB:Q9HC16 |
| Chain | Residue | Details |
| A | TYR222 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:36598981 |
| Chain | Residue | Details |
| A | GLN274 | |
| A | MET337 |
