8TS4
Crystal structure of T. Brucei hypoxanthine guanine phosphoribosyltransferase in complex with [2S,4S]-4-Guanin-9-yl-2-(2-phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 210 | 23392.9 | 2 | UniProt (Q07010) Pfam (PF00156) | Trypanosoma brucei | HGPRT,HGPRTase |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, F (A, B) | (3-{(2S,4S)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2-phosphonoethoxy)methyl]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid | non-polymer | 494.3 | 2 | Chemie (KFF) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46785.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1037.3 | |
| All* | Total formula weight | 47823.1 |
