8TS4

Crystal structure of T. Brucei hypoxanthine guanine phosphoribosyltransferase in complex with [2S,4S]-4-Guanin-9-yl-2-(2-phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Hypoxanthine-guanine phosphoribosyltransferase	polymer	210	23392.9	2	UniProt (Q07010) Pfam (PF00156) In PDB	Trypanosoma brucei	HGPRT,HGPRTase
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	(3-{(2S,4S)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2-phosphonoethoxy)methyl]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid	non-polymer		494.3	2	Chemie (KFF)
4		water	water		18.0	268	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46785.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1037.3
All*	Total formula weight	47823.1

*Water molecules are not included.