8TS4

Crystal structure of T. Brucei hypoxanthine guanine phosphoribosyltransferase in complex with [2S,4S]-4-Guanin-9-yl-2-(2-phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006166	biological_process	purine ribonucleoside salvage
A	0016757	molecular_function	glycosyltransferase activity
A	0020015	cellular_component	glycosome
A	0031981	cellular_component	nuclear lumen
A	0032264	biological_process	IMP salvage
A	0046872	molecular_function	metal ion binding
A	0052657	molecular_function	guanine phosphoribosyltransferase activity
A	0097014	cellular_component	ciliary plasm
B	0000166	molecular_function	nucleotide binding
B	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006166	biological_process	purine ribonucleoside salvage
B	0016757	molecular_function	glycosyltransferase activity
B	0020015	cellular_component	glycosome
B	0031981	cellular_component	nuclear lumen
B	0032264	biological_process	IMP salvage
B	0046872	molecular_function	metal ion binding
B	0052657	molecular_function	guanine phosphoribosyltransferase activity
B	0097014	cellular_component	ciliary plasm

Functional Information from PROSITE/UniProt

site_id	PS00103
Number of Residues	13
Details	PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VLVLEDILDTAlT

Chain	Residue	Details
A	VAL109-THR121

Functional Information from SwissProt/UniProt