8TRT

Structure of the EphA2 CRD bound to FabS1CE_C1, monoclinic form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	S1CE variant of Fab C1 heavy chain	polymer	222	23883.8	2		Homo sapiens (human)
2	G, C	S1CE variant of Fab C1 light chain	polymer	215	23432.9	2		Homo sapiens (human)
3	E, D	Ephrin type-A receptor 2	polymer	132	13961.7	2	UniProt (P29317) In PDB	Homo sapiens (human)	Epithelial cell kinase,Tyrosine-protein kinase receptor ECK
4	G, B, C	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5	B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
6		water	water		18.0	2	Chemie (HOH)

Sequence modifications

E, D: 199 - 326 (UniProt: P29317)

PDB	External Database	Details
Leu 327	-	expression tag
Val 328	-	expression tag
Pro 329	-	expression tag
Arg 330	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	122556.8
Non-Polymers*	Number of molecules	6
	Total formula weight	187.8
All*	Total formula weight	122744.6

*Water molecules are not included.