8TMU
HLA-B*73:01 bound to a 10mer peptide in complex with KIR2DL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA-B*73:01 | polymer | 277 | 32047.3 | 1 | UniProt (A0A583ZBV1) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 101 | 11936.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | Killer cell immunoglobulin-like receptor 2DL2 | polymer | 225 | 24734.6 | 1 | UniProt (P43627) Pfam (PF00047) | Homo sapiens (human) | |
| 4 | D (E) | KP1 | polymer | 10 | 1052.2 | 1 | UniProt (by SIFTS) (Q96AG3) | Homo sapiens | |
| 5 | E, G, H, I (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | J, K (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | L, M, N (A, B, C) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: A0A583ZBV1)
B: 2 - 100 (UniProt: P61769)
C: 1 - 225 (UniProt: P43627)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Leu 270 | Cys 294 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 225 | Ile 246 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 69770.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 916.9 | |
| All* | Total formula weight | 70687.4 |
