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8THR

Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Afluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporterpolymer85893850.91UniProt (Q05940)
Pfam (PF07690)
In PDB
Aequorea victoria
2A(3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-onenon-polymer317.41Chemie (EBZ)
Sequence modifications
A: -262 - 17 (PDB: 8THR)
A: 18 - 477 (UniProt: Q05940)
A: 478 - 595 (PDB: 8THR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight93850.9
Non-Polymers*Number of molecules1
Total formula weight317.4
All*Total formula weight94168.4
*Water molecules are not included.

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PDB entries from 2024-07-31

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