8T68
Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase KMT5B | polymer | 274 | 31656.8 | 1 | UniProt (Q4FZB7) Pfam (PF00856) | Homo sapiens (human) | Lysine N-methyltransferase 5B,Lysine-specific methyltransferase 5B,Suppressor of variegation 4-20 homolog 1,Su(var)4-20 homolog 1,Suv4-20h1,[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B,[histone H4]-lysine20 N-methyltransferase KMT5B |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | D (A) | 6,7-dichloro-N-[(3R)-oxolan-3-yl]-4-(pyridin-4-yl)phthalazin-1-amine | non-polymer | 361.2 | 1 | Chemie (ZKI) | |||
| 5 | E (A) | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31656.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 825.1 | |
| All* | Total formula weight | 32481.9 |
