8T68

Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042799	molecular_function	histone H4K20 methyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24396869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28114273","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2017","submissionDatabase":"PDB data bank","title":"Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor.","authors":["Halabelian L.","Tempel W.","Brown P.J.","Bountra C.","Edwards A.M.","Arrowsmith C.H."]}},{"source":"PDB","id":"3S8P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CPR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WBV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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