8SWF
Cryo-EM structure of NLRP3 open octamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 910 | 103675.7 | 8 | UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) Pfam (PF13516) | Homo sapiens (human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
Sequence modifications
A, B, C, D, E, F, G, H: 130 - 1036 (UniProt: Q96P20)
| PDB | External Database | Details |
|---|---|---|
| Ala 127 | - | expression tag |
| Glu 128 | - | expression tag |
| Tyr 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 829405.9 | |
| All* | Total formula weight | 829405.9 |
