8SH2

KLHDC2 in complex with EloB and EloC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C, A, D	Kelch domain-containing protein 2	polymer	412	46909.4	4	UniProt (Q9Y2U9) Pfam (PF13418) In PDB	Homo sapiens (human)	Hepatocellular carcinoma-associated antigen 33,Host cell factor homolog LCP,Host cell factor-like protein 1,HCLP-1
2	E, G, I, K	Elongin-B	polymer	104	11748.4	4	UniProt (Q15370) Pfam (PF00240) In PDB	Homo sapiens (human)	EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2
3	F, H, J, L	Elongin-C	polymer	96	10843.4	4	UniProt (Q15369) Pfam (PF03931) In PDB	Homo sapiens (human)	EloC, Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Transcription elongation factor B polypeptide 1

Sequence modifications

B, C, A, D: 2 - 406 (UniProt: Q9Y2U9)

PDB	External Database	Details
Gly -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	278004.9
All*	Total formula weight	278004.9

*Water molecules are not included.