8SDG

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.43

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (G, A)	Neutralizing antibody CC25.43 heavy chain	polymer	226	24064.1	2		Homo sapiens (human)
2	B, E (I, B)	Neutralizing antibody CC25.43 light chain	polymer	215	23533.1	2		Homo sapiens (human)
3	C, F (C, D)	Spike protein S1	polymer	205	23104.9	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
4	G (C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

C, D: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	141404.0
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	141625.3

*Water molecules are not included.