8S7O

M. tuberculosis gyrase holocomplex with 150 bp DNA and BDM71403

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	DNA gyrase subunit A	polymer	837	92304.2	2	UniProt (P9WG47) Pfam (PF00521) Pfam (PF03989)	Mycobacterium tuberculosis	Type IIA topoisomerase subunit GyrA
2	B, D (B, D)	DNA gyrase subunit B	polymer	678	74424.0	2	UniProt (P9WG45) Pfam (PF01751) Pfam (PF00986) Pfam (PF02518) Pfam (PF00204)	Mycobacterium tuberculosis
3	E (E)	DNA (5'-D(*CP*CP*GP*GP*AP*AP*GP*GP*GP*GP*TP*AP*AP*TP*AP*CP*T)-3')	polymer	150	46325.4	1		synthetic construct
4	F (F)	DNA (5'-D(*CP*CP*GP*GP*AP*AP*GP*GP*GP*GP*TP*AP*AP*TP*AP*CP*T)-3')	polymer	150	46291.5	1		synthetic construct
5	G (E)	6-[[2-[1-(6-methoxy-1,5-naphthyridin-4-yl)-1,2,3-triazol-4-yl]ethylamino]methyl]-4H-1,4-benzothiazin-3-one	non-polymer		447.5	1	Chemie (A1H5Q)

Sequence modifications

A, C: 2 - 838 (UniProt: P9WG47)

PDB	External Database	Details
Ile 501	Ala 501	conflict

B, D: 5 - 675 (UniProt: P9WG45)

PDB	External Database	Details
Gly -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag
Val 1	-	expression tag
Ala 2	-	expression tag
Ala 3	-	expression tag
Gln 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	426073.1
Non-Polymers*	Number of molecules	1
	Total formula weight	447.5
All*	Total formula weight	426520.6

*Water molecules are not included.