8RXB

Human UPF1 CH domain in complex with SMG6 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (E, A, D, I, L...)	Regulator of nonsense transcripts 1	polymer	173	19482.3	6	UniProt (Q92900) Pfam (PF09416)	Homo sapiens (human)	ATP-dependent helicase RENT1,Nonsense mRNA reducing factor 1,NORF1,Up-frameshift suppressor 1 homolog,hUpf1
2	B, D, F, H, J... (F, B, G, J, N...)	Telomerase-binding protein EST1A	polymer	15	1607.9	6	UniProt (Q86US8)	Homo sapiens	Ever shorter telomeres 1A,hEST1A,Nonsense mediated mRNA decay factor SMG6,Smg-6 homolog,hSmg5/7a
3	M, N, O, P, Q... (E, A, D, I, L...)	ZINC ION	non-polymer		65.4	13	Chemie (ZN)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	126541.2
Non-Polymers*	Number of molecules	13
	Total formula weight	850.3
All*	Total formula weight	127391.5

*Water molecules are not included.