8RXB
Human UPF1 CH domain in complex with SMG6 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008270 | molecular_function | zinc ion binding |
| D | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003724 | molecular_function | RNA helicase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008270 | molecular_function | zinc ion binding |
| E | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| E | 0003723 | molecular_function | RNA binding |
| E | 0003724 | molecular_function | RNA helicase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008270 | molecular_function | zinc ion binding |
| I | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| I | 0003723 | molecular_function | RNA binding |
| I | 0003724 | molecular_function | RNA helicase activity |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0008270 | molecular_function | zinc ion binding |
| L | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| L | 0003723 | molecular_function | RNA binding |
| L | 0003724 | molecular_function | RNA helicase activity |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0008270 | molecular_function | zinc ion binding |
| P | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| P | 0003723 | molecular_function | RNA binding |
| P | 0003724 | molecular_function | RNA helicase activity |
| P | 0005524 | molecular_function | ATP binding |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0008270 | molecular_function | zinc ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 192 |
| Details | Region: {"description":"C3H","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 168 |
| Details | Region: {"description":"CC/SHH/C","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 72 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19556969","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WJY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"P61406","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
