8RW1
Structure of a yeast 48S-AUC preinitiation complex in closed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (2) | 18S ribosomal RNA | polymer | 1798 | 579454.9 | 1 | Kluyveromyces lactis NRRL Y-1140 | ||
| 2 | B (A) | Small ribosomal subunit protein uS2 | polymer | 254 | 28264.5 | 1 | UniProt (Q6CN12) Pfam (PF00318) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S0 |
| 3 | C (B) | Small ribosomal subunit protein eS1 | polymer | 255 | 28971.6 | 1 | UniProt (Q6CWD0) Pfam (PF01015) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S1 |
| 4 | D (C) | Small ribosomal subunit protein uS5 | polymer | 259 | 27650.0 | 1 | UniProt (Q6CKL3) Pfam (PF00333) Pfam (PF03719) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S2 |
| 5 | E (E) | 40S ribosomal protein S4 | polymer | 261 | 29617.5 | 1 | UniProt (Q6CWJ2) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) Pfam (PF01479) | Kluyveromyces lactis NRRL Y-1140 | |
| 6 | F (G) | Small ribosomal subunit protein eS6 | polymer | 236 | 26970.4 | 1 | UniProt (Q6CM04) Pfam (PF01092) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S6 |
| 7 | G (H) | 40S ribosomal protein S7 | polymer | 190 | 21735.3 | 1 | UniProt (Q6CTD6) Pfam (PF01251) | Kluyveromyces lactis NRRL Y-1140 | |
| 8 | H (I) | 40S ribosomal protein S8 | polymer | 201 | 22642.7 | 1 | UniProt (Q6CMG3) Pfam (PF01201) | Kluyveromyces lactis NRRL Y-1140 | |
| 9 | I (J) | KLLA0E23673p | polymer | 188 | 21587.0 | 1 | UniProt (Q6CM18) Pfam (PF00163) Pfam (PF01479) | Kluyveromyces lactis NRRL Y-1140 | |
| 10 | J (L) | KLLA0A10483p | polymer | 156 | 17843.9 | 1 | UniProt (Q6CX80) Pfam (PF16205) Pfam (PF00366) | Kluyveromyces lactis NRRL Y-1140 | |
| 11 | K (N) | KLLA0F18040p | polymer | 151 | 16989.9 | 1 | UniProt (Q6CJK0) Pfam (PF08069) Pfam (PF00312) | Kluyveromyces lactis NRRL Y-1140 | |
| 12 | L (O) | Small ribosomal subunit protein uS11 | polymer | 137 | 14530.7 | 1 | UniProt (P27069) Pfam (PF00411) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S14,RP59 |
| 13 | M (V) | 40S ribosomal protein S21 | polymer | 87 | 9797.9 | 1 | UniProt (Q6CXT6) Pfam (PF01249) | Kluyveromyces lactis NRRL Y-1140 | |
| 14 | N (W) | Small ribosomal subunit protein uS8 | polymer | 130 | 14645.0 | 1 | UniProt (Q6CW21) Pfam (PF00410) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S22 |
| 15 | O (X) | KLLA0B11231p | polymer | 145 | 16047.9 | 1 | UniProt (F2Z602) Pfam (PF00164) | Kluyveromyces lactis NRRL Y-1140 | |
| 16 | P (Y) | 40S ribosomal protein S24 | polymer | 135 | 15194.5 | 1 | UniProt (Q6CU44) Pfam (PF01282) | Kluyveromyces lactis NRRL Y-1140 | |
| 17 | Q (a) | 40S ribosomal protein S26 | polymer | 119 | 13540.0 | 1 | UniProt (Q6CS01) Pfam (PF01283) | Kluyveromyces lactis NRRL Y-1140 | |
| 18 | R (b) | 40S ribosomal protein S27 | polymer | 82 | 8884.4 | 1 | UniProt (Q6CNL2) Pfam (PF01667) | Kluyveromyces lactis NRRL Y-1140 | |
| 19 | S (e) | 40S ribosomal protein S30 | polymer | 63 | 7141.4 | 1 | UniProt (Q6CUH5) Pfam (PF04758) | Kluyveromyces lactis NRRL Y-1140 | |
| 20 | T (h) | 40S ribosomal protein L41-A | polymer | 25 | 3354.2 | 1 | Kluyveromyces lactis NRRL Y-1140 | ||
| 21 | U (D) | 40S ribosomal protein S3 | polymer | 237 | 26300.5 | 1 | UniProt (Q6CRK7) Pfam (PF07650) Pfam (PF00189) | Kluyveromyces lactis NRRL Y-1140 | |
| 22 | V (F) | KLLA0D10659p | polymer | 227 | 25386.0 | 1 | UniProt (Q6CRA3) Pfam (PF00177) | Kluyveromyces lactis NRRL Y-1140 | |
| 23 | W (K) | KLLA0B08173p | polymer | 106 | 12584.4 | 1 | UniProt (Q6CVZ5) Pfam (PF03501) | Kluyveromyces lactis NRRL Y-1140 | |
| 24 | X (M) | 40S ribosomal protein S12 | polymer | 134 | 14466.4 | 1 | UniProt (Q6CLU4) Pfam (PF01248) | Kluyveromyces lactis NRRL Y-1140 | |
| 25 | Y (P) | KLLA0F07843p | polymer | 142 | 15986.8 | 1 | UniProt (Q6CKV4) Pfam (PF00203) | Kluyveromyces lactis NRRL Y-1140 | |
| 26 | Z (Q) | Small ribosomal subunit protein uS9 | polymer | 143 | 15874.5 | 1 | UniProt (Q875N2) Pfam (PF00380) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S16 |
| 27 | AA (R) | KLLA0B01474p | polymer | 136 | 15722.2 | 1 | UniProt (Q6CWU3) Pfam (PF00833) | Kluyveromyces lactis NRRL Y-1140 | |
| 28 | BA (S) | KLLA0B01562p | polymer | 146 | 17084.6 | 1 | UniProt (Q6CWT9) Pfam (PF00416) | Kluyveromyces lactis NRRL Y-1140 | |
| 29 | CA (T) | KLLA0A07194p | polymer | 144 | 15879.0 | 1 | UniProt (Q6CXM0) Pfam (PF01090) | Kluyveromyces lactis NRRL Y-1140 | |
| 30 | DA (U) | Small ribosomal subunit protein uS10 | polymer | 117 | 13337.6 | 1 | UniProt (Q6CIM1) Pfam (PF00338) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S20 |
| 31 | EA (Z) | 40S ribosomal protein S25 | polymer | 108 | 12002.1 | 1 | UniProt (Q6CW78) Pfam (PF03297) | Kluyveromyces lactis NRRL Y-1140 | |
| 32 | FA (c) | Small ribosomal subunit protein eS28 | polymer | 67 | 7549.8 | 1 | UniProt (P33285) Pfam (PF01200) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S28,S33 |
| 33 | GA (d) | Small ribosomal subunit protein uS14 | polymer | 56 | 6662.6 | 1 | UniProt (Q6CPG3) Pfam (PF00253) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S29 |
| 34 | HA (f) | Small ribosomal subunit protein eS31 | polymer | 150 | 17111.0 | 1 | UniProt (P69061) Pfam (PF00240) Pfam (PF01599) | Kluyveromyces lactis NRRL Y-1140 | 40S ribosomal protein S27a |
| 35 | IA (g) | KLLA0E12277p | polymer | 326 | 35830.9 | 1 | UniProt (Q6CNI7) Pfam (PF00400) | Kluyveromyces lactis NRRL Y-1140 | |
| 36 | JA (i) | Eukaryotic translation initiation factor 1A | polymer | 153 | 17462.2 | 1 | UniProt (P38912) Pfam (PF01176) | Saccharomyces cerevisiae S288C | eIF-1A,Eukaryotic translation initiation factor 4C,eIF-4C |
| 37 | KA (3) | mRNA (5'-R(P*AP*AP*U)-3') | polymer | 49 | 15304.9 | 1 | Kluyveromyces lactis | ||
| 38 | LA (1) | Met-tRNAi | polymer | 75 | 24714.0 | 1 | Saccharomyces cerevisiae S288C | ||
| 39 | MA (j) | Eukaryotic translation initiation factor 2 subunit alpha | polymer | 304 | 34763.7 | 1 | UniProt (P20459) Pfam (PF00575) Pfam (PF07541) | Saccharomyces cerevisiae S288C | eIF-2-alpha,eIF-2A,eIF-2alpha,eIF2-alpha |
| 40 | NA (k) | Eukaryotic translation initiation factor 2 subunit gamma | polymer | 527 | 57942.7 | 1 | UniProt (P32481) Pfam (PF00009) Pfam (PF03144) Pfam (PF09173) | Saccharomyces cerevisiae S288C | eIF2-gamma |
| 41 | OA (l) | Eukaryotic translation initiation factor 2 subunit beta | polymer | 285 | 31631.3 | 1 | UniProt (P09064) Pfam (PF01873) | Saccharomyces cerevisiae S288C | eIF2-beta |
| 42 | AB, AC, AD, AE, BB... (2, i, 3, T) | MAGNESIUM ION | non-polymer | 24.3 | 115 | Chemie (MG) | |||
| 43 | AF, XE, YE (f, a, b) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 44 | DF (k) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) | |||
| 45 | EF (k) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 46 | FF (2) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 41 |
| Total formula weight | 1358461.1 | |
| Non-Polymers* | Number of molecules | 120 |
| Total formula weight | 3661.7 | |
| All* | Total formula weight | 1362122.8 |
