8RVQ
20S proteasome from pre1-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (1, M) | Proteasome subunit beta type-6 | polymer | 222 | 24883.9 | 2 | UniProt (P23724) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
| 2 | B, K (2, N) | Proteasome subunit beta type-7 | polymer | 233 | 25945.5 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 3 | C, L (D, R) | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF00227) Pfam (PF10584) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 4 | D, M (F, T) | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 5 | E, N (G, U) | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 6 | F, O (H, V) | Proteasome subunit beta type-1 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 7 | G, P (I, W) | Proteasome subunit beta type-2 | polymer | 232 | 25114.5 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
| 8 | H, Q (J, X) | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
| 9 | I, R (L, Z) | Proteasome subunit beta type-5 | polymer | 212 | 23325.2 | 2 | UniProt (P30656) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
| 10 | S, X (A, O) | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 11 | T, Y (B, P) | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 12 | U, Z (C, Q) | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 13 | AA, V (E, S) | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 14 | BA, W (K, Y) | Proteasome subunit beta type-4 | polymer | 212 | 24431.6 | 2 | UniProt (P22141) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
| 15 | AB, BB, CA, CB, DA... (P, Q, 1, S, 2...) | water | water | 18.0 | 2412 | Chemie (HOH) |
Sequence modifications
K, Y: 1 - 198 (UniProt: P22141)
| PDB | External Database | Details |
|---|---|---|
| Phe 142 | Ser 142 | engineered mutation |
| Asp 199 | - | expression tag |
| Tyr 200 | - | expression tag |
| Lys 201 | - | expression tag |
| Asp 202 | - | expression tag |
| Asp 203 | - | expression tag |
| Asp 204 | - | expression tag |
| Asp 205 | - | expression tag |
| Lys 206 | - | expression tag |
| His 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
| His 210 | - | expression tag |
| His 211 | - | expression tag |
| His 212 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 732311.9 | |
| All* | Total formula weight | 732311.9 |
