8RIY

Human NUDT5 with ibrutinib derivative

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AAA, BBB)	ADP-sugar pyrophosphatase	polymer	209	23136.1	2	UniProt (Q9UKK9) Pfam (PF00293)	Homo sapiens (human)	8-oxo-dGDP phosphatase,Nuclear ATP-synthesis protein NUDIX5,Nucleoside diphosphate-linked moiety X motif 5,Nudix motif 5,hNUDT5,YSA1H
2	C, D (AAA, BBB)	1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine	non-polymer		400.5	2	Chemie (W0O)
3	E, F (AAA, BBB)	water	water		18.0	33	Chemie (HOH)

Sequence modifications

AAA, BBB: 1 - 208 (UniProt: Q9UKK9)

PDB	External Database	Details
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46272.2
Non-Polymers*	Number of molecules	2
	Total formula weight	801.0
All*	Total formula weight	47073.1

*Water molecules are not included.