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8RDS

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8i

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Cereblon isoform 4polymer12513703.63UniProt (A4TVL0)Magnetospirillum gryphiswaldense
2D, G, I
(A, B, C)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, H
(A, B)
(5~{S})-3-(2-methoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dionenon-polymer274.32Chemie (A1HZ6)
4F
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5J, K, L
(A, B, C)
waterwater18.041Chemie (HOH)
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
PDBExternal DatabaseDetails
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight41110.7
Non-Polymers*Number of molecules6
Total formula weight839.7
All*Total formula weight41950.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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