8RD0
HUWE1 WWE domain in complex with compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | E3 ubiquitin-protein ligase HUWE1 | polymer | 91 | 10519.6 | 4 | UniProt (Q7Z6Z7) Pfam (PF02825) | Homo sapiens (human) | |
| 2 | E, F, G, H, J... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | I, L (C, D) | (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid | non-polymer | 205.2 | 2 | Chemie (51X) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1611 - 1700 (UniProt: Q7Z6Z7)
| PDB | External Database | Details |
|---|---|---|
| Gly 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42078.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 623.1 | |
| All* | Total formula weight | 42701.3 |
