8R1F
Monomeric E6AP-E6-p53 ternary complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ubiquitin-protein ligase E3A | polymer | 899 | 103595.5 | 1 | UniProt (Q05086) Pfam (PF16558) Pfam (PF00632) In PDB | Homo sapiens (human) | E6AP ubiquitin-protein ligase,HECT-type ubiquitin transferase E3A,Human papillomavirus E6-associated protein,Oncogenic protein-associated protein E6-AP,Renal carcinoma antigen NY-REN-54 |
2 | B | Ubiquitin-like protein SMT3,Protein E6 | polymer | 266 | 31543.0 | 1 | UniProt (Q12306) UniProt (P03126) Pfam (PF00240) Pfam (PF00518) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
3 | C | Cellular tumor antigen p53 | polymer | 417 | 46495.2 | 1 | UniProt (P04637) Pfam (PF08563) Pfam (PF18521) Pfam (PF00870) Pfam (PF07710) In PDB | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
4 | B, C | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 1 - 875 (UniProt: Q05086)
B: -107 - -10 (UniProt: Q12306)
B: 1 - 158 (UniProt: P03126)
C: 1 - 393 (UniProt: P04637)
PDB | External Database | Details |
---|---|---|
Met -23 | - | initiating methionine |
Asp -22 | - | expression tag |
Trp -21 | - | expression tag |
Ser -20 | - | expression tag |
His -19 | - | expression tag |
Pro -18 | - | expression tag |
Gln -17 | - | expression tag |
Phe -16 | - | expression tag |
Glu -15 | - | expression tag |
Lys -14 | - | expression tag |
Ser -13 | - | expression tag |
Ala -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Glu -9 | - | expression tag |
Asn -8 | - | expression tag |
Leu -7 | - | expression tag |
Tyr -6 | - | expression tag |
Phe -5 | - | expression tag |
Gln -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Arg 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser -9 | - | linker |
Ala -8 | - | linker |
Asp -7 | - | linker |
Glu -6 | - | linker |
Asn -5 | - | linker |
Leu -4 | - | linker |
Tyr -3 | - | linker |
Phe -2 | - | linker |
Gln -1 | - | linker |
Gly 0 | - | linker |
PDB | External Database | Details |
---|---|---|
Ser 87 | Cys 87 | engineered mutation |
Ser 104 | Cys 104 | engineered mutation |
Ser 118 | Cys 118 | engineered mutation |
Ser 147 | Cys 147 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met -23 | - | initiating methionine |
Asp -22 | - | expression tag |
Trp -21 | - | expression tag |
Ser -20 | - | expression tag |
His -19 | - | expression tag |
Pro -18 | - | expression tag |
Gln -17 | - | expression tag |
Phe -16 | - | expression tag |
Glu -15 | - | expression tag |
Lys -14 | - | expression tag |
Ser -13 | - | expression tag |
Ala -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Glu -9 | - | expression tag |
Asn -8 | - | expression tag |
Leu -7 | - | expression tag |
Tyr -6 | - | expression tag |
Phe -5 | - | expression tag |
Gln -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Arg 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 181633.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 196.2 | |
All* | Total formula weight | 181829.9 |