8QZQ

Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Multidrug efflux pump subunit AcrB	polymer	1049	113665.2	3	UniProt (P31224) Pfam (PF00873)	Escherichia coli K-12
2	D (A)	[3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine	non-polymer		352.9	1	Chemie (XE9)
3	E (B)	[(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate	non-polymer		751.0	1	Chemie (WR6)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	340995.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1103.9
All*	Total formula weight	342099.4

*Water molecules are not included.