8QWN
Structure of p53 cancer mutant Y220C (hexagonal crystal form)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cellular tumor antigen p53 | polymer | 219 | 24530.8 | 1 | UniProt (P04637) Pfam (PF00870) In PDB | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 94 - 312 (UniProt: P04637)
PDB | External Database | Details |
---|---|---|
Leu 133 | Met 133 | engineered mutation |
Ala 203 | Val 203 | engineered mutation |
Cys 220 | Tyr 220 | engineered mutation |
Tyr 239 | Asn 239 | engineered mutation |
Asp 268 | Asn 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 24530.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 249.3 | |
All* | Total formula weight | 24780.1 |