8QQY
Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with JG165
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) In PDB | Homo sapiens (human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
2 | A | 6-(4-fluoranyl-3-methoxy-phenyl)-13$l^{6}-thia-2,4,8,12,19-pentazatricyclo[12.3.1.1^{3,7}]nonadeca-1(18),3,5,7(19),14,16-hexaene 13,13-dioxide | non-polymer | 429.5 | 1 | Chemie (WT3) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
4 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
PDB | External Database | Details |
---|---|---|
Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34462.8 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1236.4 | |
All* | Total formula weight | 35699.2 |