8QQI
E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | DNA gyrase subunit A | polymer | 524 | 58824.2 | 2 | UniProt (A0A3K0QBM9) Pfam (PF00521) UniProt (by SIFTS) (P0AES4) In PDB | Escherichia coli | |
| 2 | B, D | DNA gyrase subunit B | polymer | 801 | 89641.4 | 2 | UniProt (P0AES6) Pfam (PF02518) Pfam (PF00204) Pfam (PF01751) Pfam (PF21249) Pfam (PF18053) Pfam (PF00986) In PDB | Escherichia coli | Type IIA topoisomerase subunit GyrB |
| 3 | E | Mu217 chain E | polymer | 26 | 7943.2 | 1 | Escherichia phage Mu | ||
| 4 | F | Mu217 chain F | polymer | 26 | 8031.2 | 1 | Escherichia phage Mu | ||
| 5 | A, C | ~{N}-[[(2~{S},5~{R})-5-(4-pyridin-3-ylphenyl)pyrrolidin-2-yl]methyl]isoquinoline-5-sulfonamide | non-polymer | 444.5 | 2 | Chemie (LRL) | |||
| 6 | B, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, C: 2 - 524 (UniProt: A0A3K0QBM9)
B, D: 1 - 800 (UniProt: P0AES6)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | Met 1 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 312905.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 937.7 | |
| All* | Total formula weight | 313843.2 |
