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8QE8

Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, E, F...
(4, 5, 6, 3, 2...)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1polymer27931982.56UniProt (Q9HAN9)
Pfam (PF01467)
Homo sapiens (human)
2D, H
(A, B)
WD repeat-containing protein 26polymer64570539.82UniProt (Q9H7D7)
Pfam (PF17814)
Pfam (PF00400)
Homo sapiens (human)CUL4- and DDB1-associated WDR protein 2,Myocardial ischemic preconditioning up-regulated protein 2
3I, K
(4, 3)
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATEnon-polymer335.22Chemie (NMN)
4J, L
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
A, B: 1 - 191 (UniProt: Q9H7D7)
A, B: 192 - 645 (UniProt: Q9H7D7)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight332974.6
Non-Polymers*Number of molecules4
Total formula weight801.3
All*Total formula weight333775.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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