8QDE
Crystal structure of a truncated human L-Lactate Dehydrogenase B protein in complex with NADH and oxamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | L-lactate dehydrogenase B chain | polymer | 330 | 36609.2 | 4 | UniProt (P07195) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (human) | |
| 2 | E, K, P, U (A, B, C, D) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (NAI) | |||
| 3 | F, L, Q, V (A, B, C, D) | OXAMIC ACID | non-polymer | 89.0 | 4 | Chemie (OXM) | |||
| 4 | G, N, R (A, B, C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 5 | H, I, J, O, S... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | M (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 20 - 333 (UniProt: P07195)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
| Glu 334 | - | expression tag |
| Asn 335 | - | expression tag |
| Leu 336 | - | expression tag |
| Tyr 337 | - | expression tag |
| Phe 338 | - | expression tag |
| Gln 339 | - | expression tag |
| Gly 340 | - | expression tag |
| Leu 341 | - | expression tag |
| Glu 342 | - | expression tag |
| His 343 | - | expression tag |
| His 344 | - | expression tag |
| His 345 | - | expression tag |
| His 346 | - | expression tag |
| His 347 | - | expression tag |
| His 348 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146436.6 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 4247.0 | |
| All* | Total formula weight | 150683.7 |
