8PW1
Structure of human UCHL1 in complex with CG341 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | polymer | 227 | 25153.6 | 10 | UniProt (P09936) Pfam (PF01088) | Homo sapiens (human) | UCH-L1,Neuron cytoplasmic protein 9.5,PGP 9.5,PGP9.5,Ubiquitin thioesterase L1 |
| 2 | K, L, M, N, O... (A, B, C, D, E...) | (2~{S})-4-(iminomethyl)-1-methyl-~{N}-[1-[4-(pent-4-ynylcarbamoyl)phenyl]imidazol-4-yl]piperazine-2-carboxamide | non-polymer | 421.5 | 10 | Chemie (GKO) | |||
| 3 | AA, BA, CA, DA, U... (G, H, I, J, A...) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 223 (UniProt: P09936)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 251536.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4214.9 | |
| All* | Total formula weight | 255751.4 |
