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8PW1

Structure of human UCHL1 in complex with CG341 inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Ubiquitin carboxyl-terminal hydrolase isozyme L1polymer22725153.610UniProt (P09936)
Pfam (PF01088)
In PDB
Homo sapiens (human)UCH-L1,Neuron cytoplasmic protein 9.5,PGP 9.5,PGP9.5,Ubiquitin thioesterase L1
2A, B, C, D, E...(2~{S})-4-(iminomethyl)-1-methyl-~{N}-[1-[4-(pent-4-ynylcarbamoyl)phenyl]imidazol-4-yl]piperazine-2-carboxamidenon-polymer421.510Chemie (GKO)
3waterwater18.0227Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 223 (UniProt: P09936)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight251536.4
Non-Polymers*Number of molecules10
Total formula weight4214.9
All*Total formula weight255751.4
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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