8PTY
Cryo-EM structure of human Elp123 in complex with 5'-deoxyadenosine and methionine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Elongator complex protein 1 | polymer | 1332 | 150427.5 | 1 | UniProt (O95163) Pfam (PF04762) Pfam (PF23797) Pfam (PF23925) Pfam (PF23878) Pfam (PF23936) | Homo sapiens (human) | ELP1,IkappaB kinase complex-associated protein,IKK complex-associated protein,p150 |
| 2 | B (B) | Elongator complex protein 2 | polymer | 826 | 92597.8 | 1 | UniProt (Q6IA86) Pfam (PF00400) | Homo sapiens (human) | ELP2,SHINC-2,STAT3-interacting protein 1,StIP1 |
| 3 | C (C) | Elongator complex protein 3 | polymer | 581 | 65740.5 | 1 | UniProt (Q9H9T3) Pfam (PF23613) Pfam (PF04055) Pfam (PF16199) | Homo sapiens (human) | hELP3,tRNA uridine(34) acetyltransferase |
| 4 | D (C) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | E (C) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 1 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (71678) PubChem (23638944) PubChem (439182) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (23615209) PubChem (449044) PubChem (40467849) PubChem (1277776) PubChem (57115448) PubChem (59731278) PubChem (6398669) PubChem (6928544) PubChem (90321697) PubChem (676784) PubChem (12827542) PubChem (6541038) PubChem (121275112) PubChem (124363198) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) | |||
| 6 | F (C) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) PubChem (876) PubChem (6137) PubChem (84815) |
Sequence modifications
C: 1 - 547 (UniProt: Q9H9T3)
| PDB | External Database | Details |
|---|---|---|
| Gly 548 | - | expression tag |
| Leu 549 | - | expression tag |
| Glu 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Ser 552 | - | expression tag |
| Ala 553 | - | expression tag |
| Trp 554 | - | expression tag |
| Ser 555 | - | expression tag |
| His 556 | - | expression tag |
| Pro 557 | - | expression tag |
| Gln 558 | - | expression tag |
| Phe 559 | - | expression tag |
| Glu 560 | - | expression tag |
| Lys 561 | - | expression tag |
| Gly 562 | - | expression tag |
| Gly 563 | - | expression tag |
| Gly 564 | - | expression tag |
| Ser 565 | - | expression tag |
| Gly 566 | - | expression tag |
| Gly 567 | - | expression tag |
| Gly 568 | - | expression tag |
| Ser 569 | - | expression tag |
| Gly 570 | - | expression tag |
| Gly 571 | - | expression tag |
| Ser 572 | - | expression tag |
| Ala 573 | - | expression tag |
| Trp 574 | - | expression tag |
| Ser 575 | - | expression tag |
| His 576 | - | expression tag |
| Pro 577 | - | expression tag |
| Gln 578 | - | expression tag |
| Phe 579 | - | expression tag |
| Glu 580 | - | expression tag |
| Lys 581 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 308765.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 752.1 | |
| All* | Total formula weight | 309517.9 |
