8PJ7

MLLT3 in complex with compound PFI-6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein AF-9	polymer	148	17458.0	1	UniProt (P42568) Pfam (PF03366) In PDB	Homo sapiens (human)	ALL1-fused gene from chromosome 9 protein,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,YEATS domain-containing protein 3
2	A	~{N}-[(1~{R})-2,3-dihydro-1~{H}-inden-1-yl]-5-[4-(dimethylcarbamoyl)-3-oxidanyl-phenyl]-1,2-oxazole-3-carboxamide	non-polymer		391.4	1	Chemie (ZJ9)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
5	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
6		water	water		18.0	104	Chemie (HOH)

Sequence modifications

A: 1 - 142 (UniProt: P42568)

PDB	External Database	Details
Ala 142	Pro 142	engineered mutation
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17458.0
Non-Polymers*	Number of molecules	9
	Total formula weight	936.9
All*	Total formula weight	18395.0

*Water molecules are not included.