8PJ7
MLLT3 in complex with compound PFI-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein AF-9 | polymer | 148 | 17458.0 | 1 | UniProt (P42568) Pfam (PF03366) | Homo sapiens (human) | ALL1-fused gene from chromosome 9 protein,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,YEATS domain-containing protein 3 |
| 2 | B (A) | ~{N}-[(1~{R})-2,3-dihydro-1~{H}-inden-1-yl]-5-[4-(dimethylcarbamoyl)-3-oxidanyl-phenyl]-1,2-oxazole-3-carboxamide | non-polymer | 391.4 | 1 | Chemie (ZJ9) | |||
| 3 | C, D, E, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | J (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | K (A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: 1 - 142 (UniProt: P42568)
| PDB | External Database | Details |
|---|---|---|
| Ala 142 | Pro 142 | engineered mutation |
| His 143 | - | expression tag |
| His 144 | - | expression tag |
| His 145 | - | expression tag |
| His 146 | - | expression tag |
| His 147 | - | expression tag |
| His 148 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17458.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 936.9 | |
| All* | Total formula weight | 18395.0 |
