8PDE

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC4 deacetylase binding motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E	MEF2D protein	polymer	95	11254.0	4	UniProt (Q05BX2) Pfam (PF00319) In PDB	Homo sapiens (human)	Myocyte enhancer factor 2D
2	C, X	HDAC4 (histone deacetylase 4) binding motif peptide:GSGEVKMKLQEFVLNKK	polymer	17	1939.3	2	UniProt (by SIFTS) (P56524) In PDB	Homo sapiens
3	F, K	DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3')	polymer	14	4286.8	2		Homo sapiens
4	G, L	DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3')	polymer	14	4268.8	2		Homo sapiens
5		water	water		18.0	60	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	66006.1
All*	Total formula weight	66006.1

*Water molecules are not included.