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8PDE

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC4 deacetylase binding motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, D, E
(A, B, D, E)
MEF2D proteinpolymer9511254.04UniProt (Q05BX2)
Pfam (PF00319)
Homo sapiens (human)Myocyte enhancer factor 2D
2C, H
(C, X)
HDAC4 (histone deacetylase 4) binding motif peptide:GSGEVKMKLQEFVLNKKpolymer171939.32UniProt (by SIFTS) (P56524)Homo sapiens
3F, I
(F, K)
DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3')polymer144286.82Homo sapiens
4G, J
(G, L)
DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3')polymer144268.82Homo sapiens
5K, L, M, N, O...
(A, B, C, D, E...)
waterwater18.060Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight66006.1
All*Total formula weight66006.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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