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8OXU

Crystal Structure of the Hsp90-LA1011 Complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-dependent molecular chaperone HSP82polymer24127438.34UniProt (P02829)
Pfam (PF00183)
Saccharomyces cerevisiae (baker's yeast)82 kDa heat shock protein,Heat shock protein Hsp90 heat-inducible isoform
2E
(C)
dimethyl 2,6-bis[2-(dimethylamino)ethyl]-1-methyl-4-[4-(trifluoromethyl)phenyl]-4~{H}-pyridine-3,5-dicarboxylatenon-polymer497.61Chemie (W5R)
3F
(A)
waterwater18.01Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight109753.3
Non-Polymers*Number of molecules1
Total formula weight497.6
All*Total formula weight110250.9
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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