8OVH

Crystal structure of O-acetyl-L-homoserine sulfhydrolase from Saccharomyces cerevisiae in complex with Pyridoxal-5'-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Homocysteine/cysteine synthase	polymer	464	50897.8	4	UniProt (P06106) Pfam (PF01053)	Saccharomyces cerevisiae (baker's yeast)	O-acetylserine/O-acetylhomoserine sulfhydrylase,OAS-OAH SHLase,OAS-OAH sulfhydrylase
2	E, F, I, K (A, B, C, D)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	4	Chemie (PLP)
3	G, H, J, L (B, C, D)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
4	M, N, O, P (A, B, C, D)	water	water		18.0	482	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 444 (UniProt: P06106)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	203591.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1413.0
All*	Total formula weight	205004.2

*Water molecules are not included.