8OM6

Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Fibroblast growth factor 2	polymer	175	19531.3	1	UniProt (P09038) Pfam (PF00167) In PDB	Homo sapiens (human)	FGF-2,Basic fibroblast growth factor,bFGF,Heparin-binding growth factor 2,HBGF-2
2		water	water		18.0	128	Chemie (HOH)

Sequence modifications

A: 21 - 175 (UniProt: P09038)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Leu 51	Arg 164	conflict
Thr 72	Val 185	conflict
Asp 74	Glu 187	conflict
Phe 79	His 192	conflict
Tyr 112	Leu 225	conflict
Ile 114	Ser 227	conflict
Asn 116	Cys 229	conflict
Glu 129	Ser 242	conflict
Pro 141	Thr 254	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19531.3
All*	Total formula weight	19531.3

*Water molecules are not included.