8OM6

Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fibroblast growth factor 2	polymer	175	19531.3	1	UniProt (P09038) Pfam (PF00167)	Homo sapiens (human)	FGF-2,Basic fibroblast growth factor,bFGF,Heparin-binding growth factor 2,HBGF-2
2	B (A)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A: 1 - 155 (UniProt: P09038)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 31	Arg 164	conflict
Thr 52	Val 185	conflict
Asp 54	Glu 187	conflict
Phe 59	His 192	conflict
Tyr 92	Leu 225	conflict
Ile 94	Ser 227	conflict
Asn 96	Cys 229	conflict
Glu 109	Ser 242	conflict
Pro 121	Thr 254	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19531.3
All*	Total formula weight	19531.3

*Water molecules are not included.