8OM6
Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
Functional Information from PROSITE/UniProt
| site_id | PS00247 |
| Number of Residues | 24 |
| Details | HBGF_FGF HBGF/FGF family signature. GrLyAiknvtd.ECfFfErleennY |
| Chain | Residue | Details |
| A | GLY109-TYR132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN56 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Important for interaction with integrin => ECO:0000269|PubMed:28302677 |
| Chain | Residue | Details |
| A | LYS148 | |
| A | ARG149 | |
| A | LYS154 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by TEC => ECO:0000269|PubMed:20230531 |
| Chain | Residue | Details |
| A | TYR102 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| A | LYS115 |
