8OIX
CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor Salinosporamid A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, O | Family T1, proteasome alpha subunit, threonine peptidase | polymer | 241 | 26511.2 | 2 | UniProt (A2F568) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
2 | B, P | Family T1, proteasome alpha subunit, threonine peptidase | polymer | 232 | 25445.0 | 2 | UniProt (A2FJV7) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
3 | C, Q | Proteasome subunit alpha type | polymer | 251 | 27989.7 | 2 | UniProt (A2FT79) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
4 | D, R | Proteasome subunit alpha type | polymer | 235 | 26306.9 | 2 | UniProt (A2DTN3) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
5 | E, S | Proteasome subunit alpha type | polymer | 251 | 27331.0 | 2 | UniProt (A2FCM7) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
6 | F, T | Family T1, proteasome alpha subunit, threonine peptidase | polymer | 233 | 25682.3 | 2 | UniProt (A2E1I9) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
7 | G, U | Family T1, proteasome alpha subunit, threonine peptidase | polymer | 240 | 27067.4 | 2 | UniProt (A2D8G5) Pfam (PF10584) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
8 | H, V | Proteasome subunit beta | polymer | 204 | 21930.8 | 2 | UniProt (A2E7Z2) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
9 | I, W | proteasome endopeptidase complex | polymer | 244 | 26869.4 | 2 | UniProt (A2F2T6) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
10 | J, X | Proteasome subunit beta | polymer | 206 | 23028.6 | 2 | UniProt (A2F3H9) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
11 | K, Y | Proteasome subunit beta | polymer | 191 | 21421.6 | 2 | UniProt (A2F8W4) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
12 | L, Z | Proteasome subunit beta | polymer | 203 | 22572.6 | 2 | UniProt (A2DD57) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
13 | M, a | Proteasome subunit beta | polymer | 224 | 25001.0 | 2 | UniProt (A2F716) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
14 | N, b | Family T1, proteasome beta subunit, threonine peptidase | polymer | 244 | 26486.6 | 2 | UniProt (A2F3X4) Pfam (PF00227) In PDB | Trichomonas vaginalis G3 | |
15 | H, I, V, W | (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE | non-polymer | 279.3 | 4 | Chemie (SA1) |
Sequence modifications
N, b: 1 - 214 (UniProt: A2F3X4)
PDB | External Database | Details |
---|---|---|
Ser 215 | - | expression tag |
Ala 216 | - | expression tag |
Trp 217 | - | expression tag |
Ser 218 | - | expression tag |
His 219 | - | expression tag |
Pro 220 | - | expression tag |
Gln 221 | - | expression tag |
Phe 222 | - | expression tag |
Glu 223 | - | expression tag |
Lys 224 | - | expression tag |
Gly 225 | - | expression tag |
Gly 226 | - | expression tag |
Gly 227 | - | expression tag |
Ser 228 | - | expression tag |
Gly 229 | - | expression tag |
Gly 230 | - | expression tag |
Gly 231 | - | expression tag |
Ser 232 | - | expression tag |
Gly 233 | - | expression tag |
Gly 234 | - | expression tag |
Ser 235 | - | expression tag |
Ala 236 | - | expression tag |
Trp 237 | - | expression tag |
Ser 238 | - | expression tag |
His 239 | - | expression tag |
Pro 240 | - | expression tag |
Gln 241 | - | expression tag |
Phe 242 | - | expression tag |
Glu 243 | - | expression tag |
Lys 244 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 28 |
Total formula weight | 707288.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1117.3 | |
All* | Total formula weight | 708405.7 |