8OIX

CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor Salinosporamid A

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000502	cellular_component	proteasome complex
a	0005634	cellular_component	nucleus
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0019774	cellular_component	proteasome core complex, beta-subunit complex
a	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0000502	cellular_component	proteasome complex
A	0005634	cellular_component	nucleus
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0000502	cellular_component	proteasome complex
b	0005634	cellular_component	nucleus
b	0005829	cellular_component	cytosol
b	0019774	cellular_component	proteasome core complex, beta-subunit complex
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0000502	cellular_component	proteasome complex
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0000502	cellular_component	proteasome complex
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0000502	cellular_component	proteasome complex
H	0004175	molecular_function	endopeptidase activity
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0019774	cellular_component	proteasome core complex, beta-subunit complex
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0000502	cellular_component	proteasome complex
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0019774	cellular_component	proteasome core complex, beta-subunit complex
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0000502	cellular_component	proteasome complex
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0019774	cellular_component	proteasome core complex, beta-subunit complex
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0000502	cellular_component	proteasome complex
L	0004175	molecular_function	endopeptidase activity
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006508	biological_process	proteolysis
L	0008233	molecular_function	peptidase activity
L	0019774	cellular_component	proteasome core complex, beta-subunit complex
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0000502	cellular_component	proteasome complex
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0019774	cellular_component	proteasome core complex, beta-subunit complex
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0000502	cellular_component	proteasome complex
N	0005634	cellular_component	nucleus
N	0005829	cellular_component	cytosol
N	0019774	cellular_component	proteasome core complex, beta-subunit complex
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
O	0000502	cellular_component	proteasome complex
O	0005634	cellular_component	nucleus
O	0019773	cellular_component	proteasome core complex, alpha-subunit complex
O	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
P	0000502	cellular_component	proteasome complex
P	0019773	cellular_component	proteasome core complex, alpha-subunit complex
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0000502	cellular_component	proteasome complex
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0019773	cellular_component	proteasome core complex, alpha-subunit complex
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0000502	cellular_component	proteasome complex
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0019773	cellular_component	proteasome core complex, alpha-subunit complex
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0000502	cellular_component	proteasome complex
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0019773	cellular_component	proteasome core complex, alpha-subunit complex
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
T	0000502	cellular_component	proteasome complex
T	0019773	cellular_component	proteasome core complex, alpha-subunit complex
T	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
U	0000502	cellular_component	proteasome complex
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0019773	cellular_component	proteasome core complex, alpha-subunit complex
U	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0000502	cellular_component	proteasome complex
V	0004175	molecular_function	endopeptidase activity
V	0005634	cellular_component	nucleus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0019774	cellular_component	proteasome core complex, beta-subunit complex
V	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
X	0000502	cellular_component	proteasome complex
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0019774	cellular_component	proteasome core complex, beta-subunit complex
X	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Y	0000502	cellular_component	proteasome complex
Y	0005634	cellular_component	nucleus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0019774	cellular_component	proteasome core complex, beta-subunit complex
Y	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Z	0000502	cellular_component	proteasome complex
Z	0004175	molecular_function	endopeptidase activity
Z	0005634	cellular_component	nucleus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006508	biological_process	proteolysis
Z	0008233	molecular_function	peptidase activity
Z	0019774	cellular_component	proteasome core complex, beta-subunit complex
Z	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdrnvNtFSPdGRllQVEYAieA

Chain	Residue	Details
E	TYR8-ALA30
D	TYR4-ALA26
C	TYR5-SER27

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site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LAIqCtdGVVMASDsrtssgsfipnratn.KiteiqpkifaarcGnaAD

Chain	Residue	Details
H	LEU4-ASP51
L	LEU4-ASP51
J	LEU13-ASP60
a	ILE24-ASP71

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