8OIF
Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-like modifier-activating enzyme 7 | polymer | 1014 | 111966.2 | 1 | UniProt (P41226) Pfam (PF00899) Pfam (PF16190) Pfam (PF16191) Pfam (PF10585) Pfam (PF09358) | Homo sapiens (human) | Ubiquitin-activating enzyme 7,D8,Ubiquitin-activating enzyme E1 homolog |
| 2 | B (I) | Ubiquitin-like protein ISG15 | polymer | 157 | 17147.6 | 1 | UniProt (P05161) Pfam (PF00240) | Homo sapiens (human) | Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein,IP17,Ubiquitin cross-reactive protein,hUCRP |
| 3 | C (L) | Ubiquitin/ISG15-conjugating enzyme E2 L6 | polymer | 155 | 17912.7 | 1 | UniProt (O14933) Pfam (PF00179) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme L6,Retinoic acid-induced gene B protein,RIG-B,UbcH8,Ubiquitin carrier protein L6,Ubiquitin-protein ligase L6 |
| 4 | D (I) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (224) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (92144436) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (12358354) PubChem (122197642) PubChem (162290139) PubChem (162946266) PubChem (171699505) |
Sequence modifications
A: 1 - 1012 (UniProt: P41226)
I: 1 - 157 (UniProt: P05161)
L: 1 - 153 (UniProt: O14933)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Cys 78 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 98 | Cys 98 | conflict |
| Ser 102 | Cys 102 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 147026.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 147373.8 |
