8OH2

Structure of the Tau-PAM4 Type 1 amyloid fibril

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, B, BA, C... (A, B, C, D, E...)	Microtubule-associated protein tau	polymer	15	1437.6	36	UniProt (P10636) Pfam (PF00418)	synthetic construct	Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau
2	AB, BB, CB, DB, EB... (T, U, V, W, Y...)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j: 349 - 363 (UniProt: P10636)

PDB	External Database	Details
Ace 349	Arg 666	conflict
Nh2 363	Val 680	conflict

Contents of the asymmetric unit

Polymers	Number of chains	36
	Total formula weight	51754.4
All*	Total formula weight	51754.4

*Water molecules are not included.