8OH2
Structure of the Tau-PAM4 Type 1 amyloid fibril
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015631 | molecular_function | tubulin binding |
| B | 0015631 | molecular_function | tubulin binding |
| C | 0015631 | molecular_function | tubulin binding |
| D | 0015631 | molecular_function | tubulin binding |
| E | 0015631 | molecular_function | tubulin binding |
| F | 0015631 | molecular_function | tubulin binding |
| G | 0015631 | molecular_function | tubulin binding |
| H | 0015631 | molecular_function | tubulin binding |
| I | 0015631 | molecular_function | tubulin binding |
| J | 0015631 | molecular_function | tubulin binding |
| K | 0015631 | molecular_function | tubulin binding |
| L | 0015631 | molecular_function | tubulin binding |
| M | 0015631 | molecular_function | tubulin binding |
| N | 0015631 | molecular_function | tubulin binding |
| O | 0015631 | molecular_function | tubulin binding |
| P | 0015631 | molecular_function | tubulin binding |
| Q | 0015631 | molecular_function | tubulin binding |
| R | 0015631 | molecular_function | tubulin binding |
| S | 0015631 | molecular_function | tubulin binding |
| T | 0015631 | molecular_function | tubulin binding |
| U | 0015631 | molecular_function | tubulin binding |
| V | 0015631 | molecular_function | tubulin binding |
| W | 0015631 | molecular_function | tubulin binding |
| X | 0015631 | molecular_function | tubulin binding |
| Y | 0015631 | molecular_function | tubulin binding |
| Z | 0015631 | molecular_function | tubulin binding |
| a | 0015631 | molecular_function | tubulin binding |
| b | 0015631 | molecular_function | tubulin binding |
| c | 0015631 | molecular_function | tubulin binding |
| d | 0015631 | molecular_function | tubulin binding |
| e | 0015631 | molecular_function | tubulin binding |
| f | 0015631 | molecular_function | tubulin binding |
| g | 0015631 | molecular_function | tubulin binding |
| h | 0015631 | molecular_function | tubulin binding |
| i | 0015631 | molecular_function | tubulin binding |
| j | 0015631 | molecular_function | tubulin binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P10637 |
| Chain | Residue | Details |
| A | ACE349 | |
| J | ACE349 | |
| K | ACE349 | |
| L | ACE349 | |
| M | ACE349 | |
| N | ACE349 | |
| O | ACE349 | |
| P | ACE349 | |
| Q | ACE349 | |
| R | ACE349 | |
| S | ACE349 | |
| B | ACE349 | |
| T | ACE349 | |
| U | ACE349 | |
| V | ACE349 | |
| W | ACE349 | |
| X | ACE349 | |
| Y | ACE349 | |
| Z | ACE349 | |
| a | ACE349 | |
| b | ACE349 | |
| c | ACE349 | |
| C | ACE349 | |
| d | ACE349 | |
| e | ACE349 | |
| f | ACE349 | |
| g | ACE349 | |
| h | ACE349 | |
| i | ACE349 | |
| j | ACE349 | |
| D | ACE349 | |
| E | ACE349 | |
| F | ACE349 | |
| G | ACE349 | |
| H | ACE349 | |
| I | ACE349 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | MOD_RES: Phosphoserine; by PHK => ECO:0000269|PubMed:8999860 |
| Chain | Residue | Details |
| A | SER352 | |
| J | SER352 | |
| K | SER352 | |
| L | SER352 | |
| M | SER352 | |
| N | SER352 | |
| O | SER352 | |
| P | SER352 | |
| Q | SER352 | |
| R | SER352 | |
| S | SER352 | |
| B | SER352 | |
| T | SER352 | |
| U | SER352 | |
| V | SER352 | |
| W | SER352 | |
| X | SER352 | |
| Y | SER352 | |
| Z | SER352 | |
| a | SER352 | |
| b | SER352 | |
| c | SER352 | |
| C | SER352 | |
| d | SER352 | |
| e | SER352 | |
| f | SER352 | |
| g | SER352 | |
| h | SER352 | |
| i | SER352 | |
| j | SER352 | |
| D | SER352 | |
| E | SER352 | |
| F | SER352 | |
| G | SER352 | |
| H | SER352 | |
| I | SER352 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:7706316 |
| Chain | Residue | Details |
| A | SER356 | |
| J | SER356 | |
| K | SER356 | |
| L | SER356 | |
| M | SER356 | |
| N | SER356 | |
| O | SER356 | |
| P | SER356 | |
| Q | SER356 | |
| R | SER356 | |
| S | SER356 | |
| B | SER356 | |
| T | SER356 | |
| U | SER356 | |
| V | SER356 | |
| W | SER356 | |
| X | SER356 | |
| Y | SER356 | |
| Z | SER356 | |
| a | SER356 | |
| b | SER356 | |
| c | SER356 | |
| C | SER356 | |
| d | SER356 | |
| e | SER356 | |
| f | SER356 | |
| g | SER356 | |
| h | SER356 | |
| i | SER356 | |
| j | SER356 | |
| D | SER356 | |
| E | SER356 | |
| F | SER356 | |
| G | SER356 | |
| H | SER356 | |
| I | SER356 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 36 |
| Details | CARBOHYD: N-linked (Glc) (glycation) lysine; in PHF-tau; in vitro => ECO:0000269|PubMed:9326300 |
| Chain | Residue | Details |
| A | LYS353 | |
| J | LYS353 | |
| K | LYS353 | |
| L | LYS353 | |
| M | LYS353 | |
| N | LYS353 | |
| O | LYS353 | |
| P | LYS353 | |
| Q | LYS353 | |
| R | LYS353 | |
| S | LYS353 | |
| B | LYS353 | |
| T | LYS353 | |
| U | LYS353 | |
| V | LYS353 | |
| W | LYS353 | |
| X | LYS353 | |
| Y | LYS353 | |
| Z | LYS353 | |
| a | LYS353 | |
| b | LYS353 | |
| c | LYS353 | |
| C | LYS353 | |
| d | LYS353 | |
| e | LYS353 | |
| f | LYS353 | |
| g | LYS353 | |
| h | LYS353 | |
| i | LYS353 | |
| j | LYS353 | |
| D | LYS353 | |
| E | LYS353 | |
| F | LYS353 | |
| G | LYS353 | |
| H | LYS353 | |
| I | LYS353 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 72 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); in PHF-tau => ECO:0000269|PubMed:16443603 |
| Chain | Residue | Details |
| A | LYS353 | |
| F | LYS353 | |
| G | LYS353 | |
| H | LYS353 | |
| I | LYS353 | |
| J | LYS353 | |
| K | LYS353 | |
| L | LYS353 | |
| M | LYS353 | |
| N | LYS353 | |
| O | LYS353 | |
| B | LYS353 | |
| P | LYS353 | |
| Q | LYS353 | |
| R | LYS353 | |
| S | LYS353 | |
| T | LYS353 | |
| U | LYS353 | |
| V | LYS353 | |
| W | LYS353 | |
| X | LYS353 | |
| Y | LYS353 | |
| C | LYS353 | |
| Z | LYS353 | |
| a | LYS353 | |
| b | LYS353 | |
| c | LYS353 | |
| d | LYS353 | |
| e | LYS353 | |
| f | LYS353 | |
| g | LYS353 | |
| h | LYS353 | |
| i | LYS353 | |
| D | LYS353 | |
| j | LYS353 | |
| E | LYS353 |
